A methylxanthine alkaloid that acts as an antagonist; blocks central adenosine receptor activity at relevant physiological concentrations (IC50 = ~ 30 μM)

Caffeine – 1 g

Brand:
Cayman
CAS:
58-08-2
Storage:
-20
UN-No:
De Minimis - 1544 / 6.1

Caffeine is a methylxanthine alkaloid naturally found in various plant parts that acts as an antagonist at central adenosine receptors at relevant physiological concentrations (IC50 = ~30 μM).{17521,22196} It alters fatigue, mood, alertness, motor reaction time, vascular hemodynamics, and pain sensation.{22196,22195,22197} Caffeine has also been implicated in carcinogenesis, although the concentrations used to affect cell cycling and apoptosis in the laboratory may not be commonly achieved in vivo.{22194}  

 

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Description

A methylxanthine alkaloid that acts as an antagonist; blocks central adenosine receptor activity at relevant physiological concentrations (IC50 = ~ 30 μM)

Formal name: 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Synonyms:  Methyltheobromine|NSC 5036

Molecular weight: 194.2

CAS: 58-08-2

Purity: ≥98%

Formulation: A crystalline solid

Application||Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cancer|Cell Cycle||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Neuroscience|Behavioral Neuroscience|Addiction Research||Research Area|Neuroscience|Behavioral Neuroscience|Sleep & Biological Rhythms||Research Area|Neuroscience|Pain Research

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