C2 Adamantanyl Globotriaosylceramide (d18:1/2:0) – 1 mg

Brand:
Cayman
CAS:
261155-87-7
Storage:
-20
UN-No:
Non-Hazardous - /

C2 Adamantanyl globotriaosylceramide (AdaGb3) is a bioactive sphingolipid and water-soluble form of globotriaosylceramide (Item Nos. 24870 | 24871 | 24872) that contains an adamantanyl group in place of the fatty acyl chain.{39713} It inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay when used at a concentration of 10 μM. AdaGb3 decreases cell surface expression of P-glycoprotein (P-gp) and reduces efflux of rhodamine 123 (Item No. 16672) in MDCK cells.{39714} It also increases apical-to-basal transport of vinblastine (Item No. 11762) in human intestinal C2BBe1 cells. [Matreya, LLC. Catalog No. 1947]  

 

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SKU: 24879 - 1 mg Category:

Description

A bioactive sphingolipid; water-soluble form of globotriaosylceramide; inhibits Vero toxin binding to globotriaosylceramide in an ELISA assay (10 μM); decreases cell surface expression of P-gp and reduces efflux of rhodamine 123 in MDCK cells; increases apical-to-basal transport of vinblastine in human intestinal C2BBe1 cells,


Formal name: N-[(1S,2R,3E)-1-[[(O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl)oxy]methyl]-2-hydroxy-3-heptadecenbr-1-yl]-tricyclo[3.3.1.13,7]decane-1-acetamide

Synonyms:  AdaGb3|Adamantyl Gb3|C2 Adamantanyl Ceramide Trihexoside (d18:1/2:0)

Molecular weight: 962.2

CAS: 261155-87-7

Purity: ≥98%

Formulation: A solid


Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cancer|Multidrug Resistance||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Shigellosis||Research Area|Lipid Biochemistry|Sphingolipids