A bioactive sphingolipid; reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes; stimulates recombinant glucocerebrosidase activity in a pH-dependent manner; activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease

C2 Adamantanyl Galactosylceramide (d18:1/2:0) – 5 mg

Brand:
Cayman
CAS:
574738-16-2
Storage:
-20
UN-No:
Non-Hazardous - /

C2 Adamantanyl Galactosylceramide (d18:1/2:0) (AdaGalCer) is a bioactive sphingolipid.{38688} It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocerebrosidase activity in a pH-dependent manner. It activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively. [Matreya, LLC. Catalog No. 1946]  

 

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SKU: 24472 - 5 mg Category:

Description

A bioactive sphingolipid; reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes; stimulates recombinant glucocerebrosidase activity in a pH-dependent manner; activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively,

Formal name: N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-tricyclo[3.3.1.13,7]decane-1-acetamide

Synonyms:  AdaGalCer(d18:1/2:0)|Admantanyl Galactosylceramide (d18:1/2:0)|Admantanyl GalCer(d18:1/2:0)|N-(1-adamantaneacetyl) Galactosylceramide

Molecular weight: 637.9

CAS: 574738-16-2

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sphingolipids||Product Type|Biochemicals|Small Molecule Activators||Research Area|Endocrinology & Metabolism|Inborn Errors of Metabolism||Research Area|Lipid Biochemistry|Sphingolipids

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