A naturally occurring sphingolipid; levels are elevated in the prefrontal cortex and cerebellum in a rat model of STZ-induced diabetes

C16 Sphingomyelin (d18:1/16:0) – 10 mg

Brand:
Cayman
CAS:
6254-89-3
Storage:
-20
UN-No:
Non-Hazardous - /

C16 Sphingomyelin is a naturally occurring sphingolipid.{37418,40751,37417} Levels of C16 sphingomyelin are elevated in the prefrontal cortex and cerebellum in a rat model of diabetes induced by streptozotocin (STZ; Item No. 13104), as well as in the liver in mouse models of Niemann-Pick type C1 disease.{37418,40751} Plasma levels of C16 sphingomyelin are decreased in patients with prostate cancer.{37417} Model membranes containing C16 sphingomyelin, 1-palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC; Item No. 15102), and cholesterol (Item No. 9003100) have been used in the study of lipid raft dynamics and membrane organization.{48564,48565}  

 

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SKU: 10007946 - 10 mg Category:

Description

A naturally occurring sphingolipid; levels are elevated in the prefrontal cortex and cerebellum in a rat model of STZ-induced diabetes, as well as in the liver in mouse models of Niemann-Pick type C1 disease; plasma are decreased in patients with prostate cancer; has been used in model membranes with POPC and cholesterol in the study of lipid raft dynamics and membrane organization

Formal name: 4-hydroxy-7S-[(1R,2E)-1-hydroxy-2-hexadecen-1-yl]-N,N,N-trimethyl-9-oxo-3,5-dioxa-8-aza-4-phosphatetracosan-1-aminium, 4-oxide, inner salt

Synonyms:  N-Palmitoyl-D-erythro-Sphingosylphosphorylcholine|Palmitoyl Sphingomyelin|SM(d18:1/16:0)|Sphingomyelin (d18:1/16:0)

Molecular weight: 703

CAS: 6254-89-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cancer||Research Area|Endocrinology & Metabolism|Inborn Errors of Metabolism||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Lipid Biochemistry|Sphingolipids||Research Area|Neuroscience

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