An internal standard for the quantification of C16 ceramide by GC- or LC-MS

C16 Ceramide-d7 (d18:1-d7/16:0) – 1 mg

Brand:
Cayman
CAS:
1840942-13-3
Storage:
-20
UN-No:
Non-Hazardous - /

C16 Ceramide-d7 is intended for use as an internal standard for the quantification of C16 ceramide (Item No. 10681) by GC- or LC-MS. C16 Ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling.{18796} Accumulation of C16 ceramide through PPMP (30 μM) or MAPP (50 μM) treatment or from addition of 100 μM synthetic C16 ceramide induces apoptosis in neutrophil cultures via caspase-3 activation.{19145}  

 

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Description

An internal standard for the quantification of C16 ceramide by GC- or LC-MS

Formal name: N-[2R-hydroxy-1S-(hydroxymethyl)-3E-heptadecen-1-yl-d7]-hexadecanamide

Synonyms:  Ceramide-d7 (d18:1-d7/16:0)|Cer-d7 (d18:1-d7/16:0)|N-Palmitoyl-D-erythro-Sphingosine-d7|Palmitoyl Ceramide-d7

Molecular weight: 545

CAS: 1840942-13-3

Purity: ≥99% deuterated forms (d1-d7)

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Lipid Biochemistry|Sphingolipids

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