A fluorogenic substrate for YFV NS3 or DV NS2B/3 serine proteases; AMC is released upon enzymatic cleavage by YFV NS3 or DV NS2B/3 serine proteases and its fluorescence can be used to quantify YFV NS3 or DV NS2B/3 serine protease activity; ex/em = 340-360/440-460 nm

Bz-Nle-KRR-AMC (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
863975-32-0
Storage:
-20
UN-No:
Non-Hazardous - /

Bz-Nle-KRR-AMC is a fluorogenic peptide substrate for yellow fever virus (YFV) non-structural 3 (NS3) and dengue virus (DV) NS2B/3 serine proteases.{46461,46462} Upon enzymatic cleavage by YFV NS3 or DV NS2B/3 serine proteases, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify YFV NS3 or DV NS2B/3 serine protease activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.  

 

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SKU: 27710 - 5 mg Category:

Description

A fluorogenic substrate for YFV NS3 or DV NS2B/3 serine proteases; AMC is released upon enzymatic cleavage by YFV NS3 or DV NS2B/3 serine proteases and its fluorescence can be used to quantify YFV NS3 or DV NS2B/3 serine protease activity; ex/em = 340-360/440-460 nm, respectively

Formal name: N-benzoyl-L-norleucyl-L-lysyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide, hydrochloride

Synonyms:  Benzoyl-Nle-Lys-Arg-Arg-7-amino-4-methylcoumarin|Benzoyl-Nle-Lys-Arg-Arg-AMC|Bz-Nle-Lys-Arg-Arg-AMC

Molecular weight: 833

CAS: 863975-32-0

Purity: ≥95%

Formulation: A solid

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Dengue||Research Area|Infectious Disease|Viral Diseases|Yellow Fever

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