An antifungal agent; has broad-spectrum activity against dermatophytes (MICs = 0.0015-0.05 µg/ml)

Butenafine (hydrochloride) – 1 g

Brand:
Cayman
CAS:
101827-46-7
Storage:
-20
UN-No:
Non-Hazardous - /

Butenafine is a benzylamine antifungal agent that has broad-spectrum activity against 87 strains of dermatophytes (MICs = 0.0015-0.05 µg/ml), 15 strains of Aspergillus (MICs = 0.025-0.78 µg/ml), 4 strains of Cryptococcus (MICs = 0.78-1.56 µg/ml), and 67 strains of Candida (MICs = 3.13 to >100 µg/ml).{38473} It acts by inhibiting squalene epoxidase.{38472} Butenafine (50 µM) inhibits the synthesis of ergosterol (Item No. 19850), a sterol in the cell membranes of fungi. Formulations containing butenafine have been used in the treatment of tinea pedis, tinea corporis, and tinea cruris.  

 

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SKU: 23797 - 1 g Category:

Description

An antifungal agent; has broad-spectrum activity against dermatophytes (MICs = 0.0015-0.05 µg/ml), Aspergillus (MICs = 0.025-0.78 µg/ml), Cryptococcus (MICs = 0.78-1.56 µg/ml), and Candida (MICs = 3.13 to >100 µg/ml); inhibits squalene epoxidase; inhibits the synthesis of ergosterol when used at a concentration of 50 µM

Formal name: N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-1-naphthalenemethanamine, monohydrochloride

Synonyms: 

Molecular weight: 353.9

CAS: 101827-46-7

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Aspergillosis||Research Area|Infectious Disease|Fungal Diseases|Candidiasis

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