An internal standard for the quantification of bumetanide by GC- or LC-MS

Bumetanide-d5 – 500 µg

Brand:
Cayman
CAS:
1216739-35-3
Storage:
-20
UN-No:
Non-Hazardous - /

Bumetanide-d5 is intended for use as an internal standard for the quantification of bumetanide (Item No. 14630) by GC- or LC-MS. Bumetanide is a loop diuretic with good absorption and pharmacodynamic properties.{23240,23239} It acts as an inhibitor of the Na-K-Cl cotransporter 1 (NKCC1) and the kidney-specific NKCC2 (Kis = 0.5 and 59 μM for human and rabbit NKCC1, respectively).{23243,23244} Bumetanide also inhibits several isoforms of carbonic anhydrase.{23242}  

 

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SKU: 26773 - 500 µg Category:

Description

An internal standard for the quantification of bumetanide by GC- or LC-MS

Formal name: 3-(aminosulfonyl)-5-(butylamino)-4-phenoxy-d5-benzoic acid

Synonyms: 

Molecular weight: 369.4

CAS: 1216739-35-3

Purity: ≥99% deuterated forms (d1-d5)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Small Molecule Inhibitors|Carbonic Anhydrase||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Cardiovascular System|Kidney & Renal Disease

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