BTC AM – 1 mg

Brand:
Cayman
CAS:
176767-94-5
Storage:
-20
UN-No:
Non-Hazardous - /

BTC AM is a cell-permeable acetoxy-methyl ester of BTC (Item No. 20423). As BTC AM enters cells, it is hydrolyzed by intracellular esterases to produce BTC. BTC is a low affinity calcium indicator (Kd = 7-26 µM) that displays excitation/emission spectra of 401/529 nm, respectively. It exhibits a shift in the excitation maximum from approximately 480 to 401 nm upon calcium binding, enabling determination of ratiometric calcium measurements.{22804} BTC is suitable for detecting elevated calcium levels associated with activation of smooth muscle, neurons, and intracellular calcium stores.{22804,31960}  

 

Available on backorder

SKU: 20424 - Category:

Description

A cell-permeable acetoxy-methyl ester of BTC,


Formal name: N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-N-[3-(2-benzothiazolyl)-6-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-2-oxo-2H-1-benzopyran-7-yl]-glycine(acetyloxy)methyl ester

Synonyms: 

Molecular weight: 979.9

CAS: 176767-94-5

Purity: ≥90%

Formulation: A solid


Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Neuroscience