A substrate and inhibitor of OATP1B1

Bromosulfalein – 1 g

Brand:
Cayman
CAS:
71-67-0
Storage:
-20
UN-No:
Non-Hazardous - /

Bromosulfalein has been commonly used as both a substrate and inhibitor of organic anionic transporting polypeptide 1B1 (OATP1B1), OATP1B3, OATP1A2, and OATP2B1, as well as multidrug resistance protein 2 (MDR2).{36993,23995,23994,36994,36995,36996} It has also been used for in vivo studies of liver and biliary system function and as an anionic dye for the quantitative estimation of protein levels in tissue homogenates or purified samples.{36997,36998,36999}  

 

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Description

A substrate and inhibitor of OATP1B1, OATP1B3, OATP1A2, OATP2B1 and MDR2; has been used for in vivo studies of liver and biliary system function and as an anionic dye for the quantitative estimation of protein levels in tissue homogenates or purified samples

Formal name: 3,3′-(4,5,6,7-tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis[6-hydroxy-benzenesulfonic acid, disodium salt

Synonyms:  Bromosulfophthalein|Bromosulphalein|Sulfobromophthalein|Sulphobromophthalein

Molecular weight: 838

CAS: 71-67-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Endocrinology & Metabolism||Research Area|Toxicology|Drug Metabolism

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