A dibrominated derivative of chloramphenicol; inhibits rat liver mitochondrial and E. coli protein synthesis by 90.6 and 98.8%

Bromamphenicol – 5 mg

Brand:
Cayman
CAS:
17371-30-1
Storage:
-20
UN-No:
Non-Hazardous - /

Bromamphenicol is a dibrominated derivative of the antibiotic chloramphenicol.{42777} It inhibits rat liver mitochondrial and E. coli protein synthesis by 90.6 and 98.8%, respectively, when used at a concentration of 93 μM, and inhibits DNA synthesis in human lymphoblastoid cells by 83% at 1 mM. Bromamphenicol can also bind to the major adhesin subunit DraE from E. coli.{42778}  

 

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SKU: 28016 - 5 mg Category:

Description

A dibrominated derivative of chloramphenicol; inhibits rat liver mitochondrial and E. coli protein synthesis by 90.6 and 98.8%, respectively, at 93 μM, and inhibits DNA synthesis in human lymphoblastoid cells by 83% at 1 mM; can bind to the major adhesin subunit DraE from E. coli

Formal name: [R-(R*,R*)]-2,2-dibromo-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamide

Synonyms: 

Molecular weight: 412

CAS: 17371-30-1

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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