A dye which stains proteins in gels with ease and sensitivity; used in the Bradford to quantify the amount of protein in a solution; selectively inhibits P2X7 (IC50s = 10.1 nM and 265 nM for rat and human P2X7

Brilliant Blue G – 25 g

Brand:
Cayman
CAS:
6104-58-1
Storage:
22
UN-No:
Non-Hazardous - /

Brilliant Blue G is a dye which is commonly used in laboratories to stain or quantify proteins. A variety of methods have been developed for using Brilliant Blue G to stain gels with ease and sensitivity.{22767,22770,22766,22771} The Bradford assay is a standard, rapid dye-binding assay that uses Brilliant Blue G to quantify the amount of protein in a solution.{11189} This compound also acts as a selective inhibitor of the P2X purinoceptor channel P2X7 (IC50s = 10.1 and 265 nM for rat and human P2X7, respectively).{22768} In mice, it inhibits interleukin-1β expression and reduces neurological injury secondary to traumatic brain injury.{22769}  

 

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Description

A dye which stains proteins in gels with ease and sensitivity; used in the Bradford to quantify the amount of protein in a solution; selectively inhibits P2X7 (IC50s = 10.1 nM and 265 nM for rat and human P2X7, respectively) and reduces neurological injury secondary to traumatic brain injury in mice

Formal name: N-[4-[[4-[(4-ethoxyphenyl)amino]phenyl][4-[ethyl[(3-sulfophenyl)methyl]amino]-2-methylphenyl]methylene]-3-methyl-2,5-cyclohexadien-1-ylidene]-N-ethyl-3-sulfo-benzenemethanaminium, sodium salt

Synonyms:  Acid Blue 90|CBBG|Coomassie Brilliant Blue G-250|NSC 328382

Molecular weight: 854

CAS: 6104-58-1

Purity:

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Research Area|Neuroscience|Neuroprotection

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