An inducer of PDX1 expression; increases PDX1 and insulin gene expression in PANC-1 cells; increases PDX1 protein levels in PANC-1 cells; increases histone H3 acetylation and trimethylation of H3K4 and H3K9

BRD7552 – 5 mg

Brand:
Cayman
CAS:
1137359-47-7
Storage:
-20
UN-No:
Non-Hazardous - /

BRD7552 is a small molecule that induces expression of pancreatic and duodenal homeobox 1 (PDX1), a transcription factor involved in pancreas development and function.{40044} BRD7552 dose-dependently increases PDX1 and insulin gene expression, as well as PDX1 protein levels, in PANC-1 cells. It also increases acetylation of histone H3 and trimethylation of H3K4 and H3K9.  

 

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Description

An inducer of PDX1 expression; increases PDX1 and insulin gene expression in PANC-1 cells; increases PDX1 protein levels in PANC-1 cells; increases histone H3 acetylation and trimethylation of H3K4 and H3K9,

Formal name: 2,3-bis(N-1,3-benzodioxol-5-ylcarbamate), 4-[N-[4-(ethoxycarbonyl)phenyl]carbamate], methyl, α-D-glucopyranoside

Synonyms: 

Molecular weight: 711.6

CAS: 1137359-47-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Transcription Factors & Coactivators||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes

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