A quinazoline that inhibits the tyrosine kinase activity of EGFR (IC50 = 0.025 nM); inhibits the growth of SKOV3 and MDA-468 tumor cell lines (EC50s = 6.5 and 30 µM

BPIQ-I – 5 mg

Brand:
Cayman
CAS:
174709-30-9
Storage:
-20
UN-No:
Non-Hazardous - /

BPIQ-I is a quinazoline that inhibits the tyrosine kinase activity of the epidermal growth factor receptor (IC50 = 0.025 nM).{28434} It can inhibit the growth of SKOV3 and MDA-468 tumor cell lines with EC50 values of 6.5 and 30 µM, respectively.{23691}  

 

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Description

A quinazoline that inhibits the tyrosine kinase activity of EGFR (IC50 = 0.025 nM); inhibits the growth of SKOV3 and MDA-468 tumor cell lines (EC50s = 6.5 and 30 µM, respectively)

Formal name: N-(3-bromophenyl)-3-methyl-3H-imidazo[4,5-g]quinazolin-8-amine

Synonyms:  PD 159121

Molecular weight: 354.2

CAS: 174709-30-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|EGFR/ErbB/HER Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|Growth Factor Receptor Signaling

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