A Cdk inhibitor (IC50s = 4.6

Bohemine – 1 mg

Brand:
Cayman
CAS:
189232-42-6
Storage:
-20
UN-No:
Non-Hazardous - /

Bohemine is a purine derivative that inhibits cyclin-dependent kinases (Cdks) (IC50s = 4.6, 8.3, and 2.7 µM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively).{32887} It has been shown to suppress cell growth and induce G1 and G2 phase cell cycle arrest in hybridoma cells.{32886}  

 

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Description

A Cdk inhibitor (IC50s = 4.6, 8.3, and 2.7 µM for Cdk2/cyclin E, Cdk2/cyclin A, Cdk9/cyclin T1, respectively); suppresses tumor cell growth, inducing G1 and G2 phase cell cycle arrest

Formal name: 3-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-propanol

Synonyms: 

Molecular weight: 340.4

CAS: 189232-42-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|CDKs||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Cycle

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