An ECM peptide conjugated to biotin; stimulates the production of collagen IV and laminin in dermal and epidermal cells ex vivo; induces proliferation of keratinocytes and increases hair growth by 58 and 121% compared with control follicles at 2 and 5 ppm

Biotin Tripeptide-1 – 25 mg

Brand:
Cayman
CAS:
299157-54-3
Storage:
-20
UN-No:
Non-Hazardous - /

Biotin tripeptide-1 is an extracellular matrix (ECM) peptide that has been conjugated to biotin (Item No. 22582).{47444} It stimulates the production of collagen IV and laminin in dermal and epidermal cells ex vivo. Biotin tripeptide-1 localizes to the peri-pilial zone of isolated cultured human hair follicles, induces proliferation of keratinocytes, and increases hair growth by 58 and 121% compared with control follicles when used at concentrations of 2 and 5 ppm, respectively.{47445} It also prevents decreases in the collagen IV and laminin 5 bands of isolated cultured hair follicles.  

 

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SKU: 27153 - 25 mg Category:

Description

An ECM peptide conjugated to biotin; stimulates the production of collagen IV and laminin in dermal and epidermal cells ex vivo; induces proliferation of keratinocytes and increases hair growth by 58 and 121% compared with control follicles at 2 and 5 ppm, respectively; prevents decreases in the collagen IV and laminin 5 bands of isolated cultured hair follicles

Formal name: N-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]glycyl-L-histidyl-L-lysine

Synonyms:  Biotinoyl Tripeptide-1|Biotinyl-GHK|Biotinyl-Gly-His-Lys

Molecular weight: 566.7

CAS: 299157-54-3

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Peptides||Research Area|Cell Biology|ECM & Adhesion Molecules

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