A yellow breakdown product of heme catabolism

Bilirubin – 5 g

Brand:
Cayman
CAS:
635-65-4
Storage:
-20
UN-No:
Non-Hazardous - /

Bilirubin is a yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase.{28325} This reaction produces carbon monoxide and biliverdin, which is rapidly reduced to bilirubin by biliverdin reductase. Bilirubin has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions.{28325} Free and albumin-bound bilirubin can also scavenge nitric oxide (NO) and NO-related species. Unconjugated bilirubin is highly water-insoluble and must be conjugated with glucuronides to become water soluble and subsequently excreted by the liver and kidney.{28325}  

 

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Description

A yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase; has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions

Formal name: 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid

Synonyms:  Hematoidin|NSC 26685

Molecular weight: 584.7

CAS: 635-65-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Immunology & Inflammation||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen

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