A synthetic pyrethroid insecticide; prolongs opening of sodium channels resulting in membrane depolarization and conductance block in the insect nervous system; effective against A. gambiae and C. quinquefasciatus mosquitos (LD50s = 0.15 and 0.16 ng/mg

Bifenthrin – 50 mg

Brand:
Cayman
CAS:
82657-04-3
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Bifenthrin is a synthetic pyrethroid insecticide that prolongs opening of sodium channels resulting in membrane depolarization and conductance block in the insect nervous system.{36375} It is effective against A. gambiae and C. quinquefasciatus mosquitos (LD50s = 0.15 and 0.16 ng/mg, respectively) and increases O. insidiosus mortality in treated corn and sorghum plants.{41760,41761} Bifenthrin exhibits aquatic toxicity, inducing reproductive defects and lethality in D. magna (LC50 = 12.4 µg/L).{41762} Acute oral administration of bifenthrin induces fine tremor, decreases motor activity and grip strength, and increases pawing and head shaking behaviors in rats, indicating typical Type I pyrethroid neurotoxicity.{41763} Bifenthrin (8 mg/kg) also decreases locomotor activity, induces anemia, elevates white blood cell counts, alanine transaminase (ALT), and superoxide dismutase (SOD), as well as decreases glutathione peroxidase (Gpx) activity in mice.{41764}  

 

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Description

A synthetic pyrethroid insecticide; prolongs opening of sodium channels resulting in membrane depolarization and conductance block in the insect nervous system; effective against A. gambiae and C. quinquefasciatus mosquitos (LD50s = 0.15 and 0.16 ng/mg, respectively); increases O. insidiosus mortality in treated corn and sorghum plants; induces fine tremor, decreases motor activity and grip strength, and increases pawing and head shaking behaviors in rats; decreases locomotor activity, induces anemia, elevates white blood cell counts, ALT and SOD, as well as decreases Gpx activity in mice at 8 mg/kg

Formal name: (1R,3R)-rel-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethyl-cyclopropanecarboxylic acid, (2-methyl[1,1′-biphenyl]-3-yl)methyl ester

Synonyms:  (±)-Bifenthrin

Molecular weight: 422.9

CAS: 82657-04-3

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Ion Channel Modulation||Product Type|Biochemicals|Pesticides|Insecticides||Research Area|Neuroscience||Research Area|Toxicology|Environmental|Aquatic Systems

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