Bicyclo PGE2 is a stable

Bicyclo Prostaglandin E2 – 1 mg

Brand:
Cayman
CAS:
74158-09-1
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Bicyclo prostaglandin E2 (bicyclo PGE2) is a stable breakdown product of PGE2 (Item No. 14010) and 13,14-dihydro-15-keto PGE2 (Item No. 14650). Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2 found in human plasma at a median level of 20-25 pg/ml.{182,4383} Due to the inherent instability of 13,14-dihydro-15-keto PGE2, it is advisable to quantify it as bicyclo PGE2 to estimate PGE2 biosynthesis or metabolism in vivo.{2571,581}  

 

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Description

Bicyclo PGE2 is a stable, base-catalyzed transformation product of 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 itself is a metabolite of PGE2{182} found in human plasma at a median level of 20-25 pg/ml.{4383} Due to the inherent instability of 13,14-dihydro-15-keto PGE2, it is advisable to quantify it as bicyclo PGE2 to estimate PGE2 biosynthesis or metabolism in vivo.{2571,581}

Formal name: 11-deoxy-13,14-dihydro-15-keto-11β,16.xi.-cycloprostaglandin E2

Synonyms:  Bicyclo PGE2

Molecular weight: 334.5

CAS: 74158-09-1

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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