An active metabolite of BIBF 1120; inhibits VEGFR2 (IC50 = 62 nM)

BIBF 1202 – 5 mg

Brand:
Cayman
CAS:
894783-71-2
Storage:
-20
UN-No:
Non-Hazardous - /

BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; Item No. 11022).{20204,47489} It is formed from BIBF 1120 by intracellular esterases.{20204} BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.  

 

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SKU: 27176 - 5 mg Category:

Description

An active metabolite of BIBF 1120; inhibits VEGFR2 (IC50 = 62 nM)

Formal name: (3Z)-2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid

Synonyms: 

Molecular weight: 525.6

CAS: 894783-71-2

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Kinase Inhibitors|FGFR Family||Product Type|Biochemicals|Kinase Inhibitors|PDGFR Family||Product Type|Biochemicals|Kinase Inhibitors|SRC Family||Product Type|Biochemicals|Kinase Inhibitors|VEGFR Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cancer|Angiogenesis||Research Area|Cancer|Cell Signaling|Growth Factor Receptor Signaling||Research Area|Cancer|Cell Signaling|SRC Family Signaling||Research Area|Immunology & Inflammation|Pulmonary Diseases||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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