Description
A glycoside with diverse biological activities; scavenges DPPH and ABTS radicals and inhibits nitrite production in vitro from 0.1-3 mM; induces production of TNF-α, NO, and IL-12 in M. tuberculosis-infected macrophages; reduces pulmonary lesion formation and bacterial load in mice infected with M. tuberculosis H37Rv; restores activity of mitochondrial complex I, II, and IV and reduces renal lipid peroxidation, IL-1β production, and shrinkage of glomeruli in a rat model of ethylene glycol-induced renal injury at 10 mg/kg; prevents arrhythmias induced by coronary artery ligation and reperfusion and BaCl2 in mice
Formal name: (2R,3S,4S,4aR,10bS)-3,4,4a,10b-tetrahydro-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-pyrano[3,2-c][2]benzopyran-6(2H)-one
Synonyms: (–)-Bergenin|Cuscutin|NSC 661749
Molecular weight: 328.3
CAS: 477-90-7
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cardiovascular System|Heart|Arrhythmia||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis
