An alkaloid natural product that reduces total cholesterol

Berberine – 50 g

Brand:
Cayman
CAS:
633-65-8
Storage:
-20
UN-No:
Non-Hazardous - /

Berberine is a widely distributed berberidaceaen alkaloid found in Berberis, H. canadensis, X. simplicissima, P. amurense, C. chinensis, T. cordifolia, A. mexicana, and E. californica that has been employed in traditional medicine as an antiprotozoal and antidiarrheal agent. Berberine reduces total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides in both humans (at 1 g/day) and hamsters fed 50 mg/kg/day along with a high fat diet.{12390} Berberine does not act through 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibition, but instead enhances LDL-receptor protein and mRNA levels in hepatocytes. Berberine is therefore a natural product that may help control serum cholesterol without the side effects typical of the statin family of hypocholesterolemic drugs.  

 

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SKU: 10006427 - 50 g Category:

Description

An alkaloid natural product that reduces total cholesterol, LDL cholesterol, and triglycerides in humans and hamsters; enhances LDL-receptor protein and mRNA levels in hepatocytes

Formal name: 5,6-dihydro-9,10-dimethoxy-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, chloride

Synonyms:  BBR|Umbellatine

Molecular weight: 371.8

CAS: 633-65-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antiparasitics||Product Type|Biochemicals|Natural Products|Alkaloids||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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