An ACE inhibitor; active metabolite of the prodrug benazepril

Benazeprilat – 1 mg

Brand:
Cayman
CAS:
86541-78-8
Storage:
-20
UN-No:
Non-Hazardous - /

Benazeprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 0.28 nM in plasma from dog) and the active metabolite of the prodrug benazepril.{38021} Benazeprilat is produced in the liver following cleavage of the ester group from benazepril. Formulations containing the prodrug benazepril have been used to treat hypertension in human and veterinary medicine.  

 

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Description

An ACE inhibitor; active metabolite of the prodrug benazepril,

Formal name: (3S)-3-[[(1S)-1-carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid

Synonyms:  CGS 14831

Molecular weight: 396.4

CAS: 86541-78-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Angiotensin-converting Enzyme||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension

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