A clickable PAD inhibitor; inhibits PAD1-4 (Kinact/KI values of 900

BB-F-Yne – 500 µg

Brand:
Cayman
CAS:
2219331-30-1
Storage:
-20
UN-No:
Non-Hazardous - /

BB-F-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine (Item No. 17079) that contains an alkyne moiety for use in click chemistry reactions.{43084} BB-F-Yne inhibits PAD1-4 with Kinact/KI values of 900, 1,200, 3,400, and 3,750 M-1min-1, respectively. It has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.  

 

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SKU: 25379 - 500 µg Category:

Description

A clickable PAD inhibitor; inhibits PAD1-4 (Kinact/KI values of 900, 1,200, 3,400, and 3,750 M-1min-1, respectively); has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters

Formal name: N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-fluoro-1-iminoethyl)amino]butyl]-4′-ethynyl-[1,1′-biphenyl]-4-carboxamide

Synonyms: 

Molecular weight: 467.5

CAS: 2219331-30-1

Purity: ≥98%

Formulation: A crystalline solid

Application|Click Chemistry||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Product Type|Biochemicals|Small Molecule Inhibitors|Deiminases||Research Area

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