A cell-permeable derivative of BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions; inhibits PAD1-4 (Kinact/KI values of 6

BB-Cl-Yne – 1 mg

Brand:
Cayman
CAS:
2219324-71-5
Storage:
-20
UN-No:
Non-Hazardous - /

BB-Cl-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine (Item No. 17079) that contains an alkyne moiety for use in click chemistry reactions.{43084} BB-Cl-Yne inhibits PAD1-4 with Kinact/KI values of 6,400, 3,600, 10,800, and 4,900 M-1min-1, respectively. It has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.  

 

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SKU: 25378 - 1 mg Category:

Description

A cell-permeable derivative of BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions; inhibits PAD1-4 (Kinact/KI values of 6,400, 3,600, 10,800, and 4,900 M-1min-1, respectively); has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters

Formal name: N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-4′-ethynyl-[1,1′-biphenyl]-4-carboxamide

Synonyms: 

Molecular weight: 484

CAS: 2219324-71-5

Purity: ≥98%

Formulation: A crystalline solid

Application|Click Chemistry||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Product Type|Biochemicals|Small Molecule Inhibitors|Deiminases||Research Area

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