A partial agonist of CB1 and CB2 (Kis = 55.4

BAY 59-3074 – 10 mg

Brand:
Cayman
CAS:
406205-74-1
Storage:
-20
UN-No:
Non-Hazardous - /

BAY 59-3074 is a partial agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 55.4, 48.3, and 45.5 nM for rat CB1, human CB1, and human CB2, respectively).{32884} BAY 59-3074 is orally active and exhibits anti-hyperalgesic and anti-allodynic properties in rat models of chronic neuropathic and inflammatory pain.{32884,32885,12277}  

 

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Description

A partial agonist of CB1 and CB2 (Kis = 55.4, 48.3, and 45.5 nM for rat CB1, human CB1, and human CB2, respectively); exhibits anti-hyperalgesic and anti-allodynic properties in rat models of chronic neuropathic and inflammatory pain

Formal name: 4,4,4-trifluoro-1-butanesulfonic acid, 3-[2-cyano-3-(trifluoromethyl)phenoxy]phenyl ester

Synonyms: 

Molecular weight: 453.4

CAS: 406205-74-1

Purity: ≥98%

Formulation: A crystalline solid

Application||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors||Research Area|Neuroscience|Pain Research

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