A triterpenoid saponin; inhibits the growth of C. albicans

Bacopaside X – 25 mg

Brand:
Cayman
CAS:
94443-88-6
Storage:
-20
UN-No:
Non-Hazardous - /

Bacopaside X is a triterpenoid saponin that has been found in B. monniera and has antifungal and anticancer activities.{48522,48711,46395} It inhibits the growth of the fungi C. albicans, C. neoformans, and A. fumigatus (MIC = 50 µg/ml for all).{48711} Bacopaside X decreases the proliferation of MDA-MB-231, SHG44, HCT8, A549, and PC3M cancer cell lines with IC50 values of 14.3, 15.9, 9.8, 9.7, and 10.1 µM, respectively.{46395} It reduces tumor growth by 84.13% in an S180 sarcoma mouse allograft model when administered at a dose of 50 µmol/kg.  

 

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SKU: 11851 - 25 mg Category:

Description

A triterpenoid saponin; inhibits the growth of C. albicans, C. neoformans, and A. fumigatus (MIC = 50 µg/ml for all); decreases the proliferation of various cancer cell lines (IC50s = 9.7-15.9 µM); reduces tumor growth by 84.13% in an S180 sarcoma mouse allograft model at 50 µmol/kg

Formal name: (3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-α-L-arabinofuranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-α-L-arabinopyranoside

Synonyms:  ​Jujubogenin isomer of Bacopasaponin C|Bacopaside VII

Molecular weight: 899.1

CAS: 94443-88-6

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Natural Products|Saponins||Product Type|Biochemicals|Natural Products|Terpenes||Research Area|Cancer||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Aspergillosis||Research Area|Infectious Disease|Fungal Diseases|Candidiasis

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