A major inactive metabolite of axitinib; formed from axitinib primarily by CYP3A4

Axitinib Sulfoxide – 5 mg

Brand:
Cayman
CAS:
1347304-18-0
Storage:
-20
UN-No:
Non-Hazardous - /

Axitinib sulfoxide is a major inactive metabolite of the tyrosine kinase inhibitor axitinib (Item No. 13813).{43878,43879} It is formed from axitinib primarily by the cytochrome P450 (CYP) isoform CYP3A4 with minor contributions from CYP3A5 and CYP2C19.{43878}  

 

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SKU: 28042 - 5 mg Category:

Description

A major inactive metabolite of axitinib; formed from axitinib primarily by CYP3A4

Formal name: N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide

Synonyms: 

Molecular weight: 402.5

CAS: 1347304-18-0

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cancer|Angiogenesis||Research Area|Cancer|Cell Signaling|Growth Factor Receptor Signaling||Research Area|Cell Biology|Cell Signaling||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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