A potent inhibitor of Aurora A kinase (IC50 = 42 nM); selective for Aurora A over BMX

Aurora Kinase Inhibitor III – 5 mg

Brand:
Cayman
CAS:
879127-16-9
Storage:
4
UN-No:
Non-Hazardous - /

Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).{25289} It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively).  

 

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Description

A potent inhibitor of Aurora A kinase (IC50 = 42 nM); selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively)

Formal name: N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-cyclopropanecarboxamide

Synonyms: 

Molecular weight: 413.4

CAS: 879127-16-9

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Kinase Inhibitors|Aurora||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|Aurora Signaling||Research Area|Cell Biology|Cell Signaling

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