A peptide analog of oxytocin that antagonizes the human oxytocin receptor (Ki = 81 nM); has tocolytic actions in the acute phase of imminent preterm birth

Atosiban – 5 mg

Brand:
Cayman
CAS:
90779-69-4
Storage:
-20
UN-No:
Non-Hazardous - /

Atosiban is a peptide analog of oxytocin (Item No. 11799) that antagonizes the human oxytocin receptor (Ki = 81 nM).{33007} It also binds the vasopressin V1a receptor (Ki = 3.5 nM).{33007} Because of its effects on the oxytocin receptor, atosiban has tocolytic actions in the acute phase of imminent preterm birth.{33008,33009,33010}  

 

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Description

A peptide analog of oxytocin that antagonizes the human oxytocin receptor (Ki = 81 nM); has tocolytic actions in the acute phase of imminent preterm birth

Formal name: cyclic (1→5)-disulfide O-ethyl-N-(3-mercapto-1-oxopropyl)-D-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-glycinamide

Synonyms:  Antocin|ORF 22164|RWJ 22164|Tractocile

Molecular weight: 994.2

CAS: 90779-69-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Peptides||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Endocrinology & Metabolism|Reproductive Biology

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