An internal standard for the quantification of atorvastatin by GC- or LC-MS

Atorvastatin-d5 (calcium salt) – 500 µg

Brand:
Cayman
CAS:
222412-82-0
Storage:
-20
UN-No:
Non-Hazardous - /

Atorvastatin-d5 is intended for use as an internal standard for the quantification of atorvastatin (Item No. 10493) by GC- or LC-MS. Atorvastatin is an inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol synthesis, that has IC50 values of 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively.{37553} Formulations containing atorvastatin have been used in the treatment of hypercholesterolemia and certain dyslipidemias.  

 

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SKU: 25043 - 500 µg Category:

Description

An internal standard for the quantification of atorvastatin by GC- or LC-MS

Formal name: 2-(4-fluorophenyl)-βR,δR-dihydroxy-5-(1-methylethyl)-3-(phenyl-d5)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, hemicalcium salt

Synonyms: 

Molecular weight: 582.7

CAS: 222412-82-0

Purity: ≥99% deuterated forms (d1 -d3)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Cholesterol Metabolism

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