(+)-Atenolol – 5 mg

Brand:
Cayman
CAS:
56715-13-0
Storage:
-20
UN-No:
Non-Hazardous - /

(+)-Atenolol is an enantiomer of the β1-adrenergic receptor (β1-AR) antagonist (±)-atenolol (Item No. 17250).{28227} (+)-Atenolol inhibits radioligand binding to β-ARs on sarcolemma-enriched membranes (Ki = 8.61 µM). Unlike (–)-atenolol and (±)-antenolol, (+)-atenolol has no effect on blood pressure in spontaneously hypertensive rats.{49503,59185}  

 

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Description

An enantiomer of (±)-atenolol; inhibits radioligand binding to β-ARs on sarcolemma-enriched membranes (Ki = 8.61 µM); has no effect on blood pressure in spontaneously hypertensive rats


Formal name: 4-[(2R)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneacetamide

Synonyms:  (R)-Atenolol

Molecular weight: 266.3

CAS: 56715-13-0

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Receptor Pharmacology||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Heart|Arrhythmia