A bioactive saponin from traditional Chinese medicine; dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 µM; LC50 = 865 µM); has diverse protective effects for the cardiovascular

Astragaloside IV – 5 mg

Brand:
Cayman
CAS:
84687-43-4
Storage:
-20
UN-No:
Non-Hazardous - /

Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.{27380} It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 µM; LC50 = 865 µM).{34673} It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems.{27380,34672} In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.{34674}  

 

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Description

A bioactive saponin from traditional Chinese medicine; dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 µM; LC50 = 865 µM); has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems; reduces myocardial infarct size in dogs

Formal name: (3β,6α,16β,20R,24S)-20,24-epoxy-16,25-dihydroxy-3-(β-D-xylopyranosyloxy)-9,19-cyclolanostan-6-yl, β-D-glucopyranoside

Synonyms:  AS-IV|AST-IV

Molecular weight: 785

CAS: 84687-43-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Saponins||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Cardiovascular System|Heart|Arrhythmia||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases||Research Area|Neuroscience|Neuroprotection

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