An aminopeptidase B inhibitor that is commonly used to characterize novel proteases

Arphamenine B (hemisulfate) – 1 mg

Brand:
Cayman
CAS:
144110-38-3
Storage:
-20
UN-No:
Non-Hazardous - /

Aminopeptidase B is a Zn2+-dependent exopeptidase that selectively removes arginine and/or lysine from the amino terminus of peptide substrates.{29942} This enzyme is a metalloprotease commonly found on the surface of mammalian cells, including macrophages and lymphocytes. Arphamenine B is an aminopeptidase B inhibitor first isolated from bacteria.{29946,29945} Like the aminopeptidase inhibitors bestatin (Item No. 70520) and amastatin (Item No. 16719), arphamenine B enhances immune responses.{29946} Arphamenine B is commonly used to characterize novel proteases.{29943,29944}  

 

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Description

An aminopeptidase B inhibitor that is commonly used to characterize novel proteases

Formal name: αR-[(3S)-3-amino-6-[(aminoiminomethyl)amino]-2-oxohexyl]-4-hydroxy-benzenepropanoic acid, hemisulfate

Synonyms: 

Molecular weight: 385.4

CAS: 144110-38-3

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Immunology & Inflammation|Innate Immunity

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