An arginase inhibitor (IC50s = 223 and 509 nM for recombinant human arginase I and II

Arginase Inhibitor 1 – 5 mg

Brand:
Cayman
CAS:
1345808-25-4
Storage:
-20
UN-No:
Non-Hazardous - /

Arginase inhibitor 1 is an inhibitor of arginase I and II (IC50s = 223 and 509 nM, respectively, for the recombinant human enzymes).{50100} It decreases arginase I activity in CHOK cells expressing human arginase I (IC50 = 8 µM). Arginase inhibitor 1 (100 mg/kg, i.v.) reduces infarct size in a rat model of myocardial ischemia and reperfusion injury induced by left-main coronary artery occlusion.  

 

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SKU: 28418 - 5 mg Category:

Description

An arginase inhibitor (IC50s = 223 and 509 nM for recombinant human arginase I and II, respectively); decreases arginase I activity in CHOK cells expressing human arginase I (IC50 = 8 µM); reduces infarct size in a rat model of myocardial ischemia and reperfusion injury induced by left-main coronary artery occlusion at 100 mg/kg, i.v.

Formal name: (αR)-α-amino-α-(4-boronobutyl)-1-piperidinebutanoic acid

Synonyms: 

Molecular weight: 286.2

CAS: 1345808-25-4

Purity: ≥95%

Formulation: A solid

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