A triterpenoid saponin with anti-inflammatory and gastroprotective activities; increases apoptosis of and decreases production of IL-1β and IL-6 in human MH7A rheumatoid arthritis fibroblast-like synoviocytes from 4-16 µM; reduces gastric acid secretion and lesion size in rat models of hydrochloric acid and ethanol-

Araloside A – 1 mg

Brand:
Cayman
CAS:
7518-22-1
Storage:
-20
UN-No:
Non-Hazardous - /

Araloside A is a triterpenoid saponin that has been found in A. taibaiensis and has anti-inflammatory and gastroprotective effects.{46919,46918} It increases apoptosis of and decreases production of IL-1β and IL-6 in human MH7A rheumatoid arthritis fibroblast-like synoviocytes when used at concentrations ranging from 4 to 16 µM.{46919} Araloside A (50 and 100 mg/kg) reduces gastric acid secretion and lesion size in rat models of hydrochloric acid and ethanol-, aspirin-, water immersion stress-, or pyloric ligation-induced ulcer formation.{46918}  

 

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SKU: 30219 - 1 mg Category:

Description

A triterpenoid saponin with anti-inflammatory and gastroprotective activities; increases apoptosis of and decreases production of IL-1β and IL-6 in human MH7A rheumatoid arthritis fibroblast-like synoviocytes from 4-16 µM; reduces gastric acid secretion and lesion size in rat models of hydrochloric acid and ethanol-, aspirin-, water immersion stress-, or pyloric ligation-induced ulcer formation at 50 and 100 mg/kg

Formal name: (3β)-28-(β-D-glucopyranosyloxy)-28-oxoolean-12-en-3-yl 4-O-α-L-arabinofuranosyl-β-D-glucopyranosiduronic acid

Synonyms:  Chikusetsusaponin 4|Chikusetsusaponin IV|Oleanoside E

Molecular weight: 927.1

CAS: 7518-22-1

Purity: ≥95%

Formulation: A crystalline solid

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