An inhibitor of FAAH attenuating the FAAH activity from mouse neuroblastoma cells with an IC50 value of 12 µM; alters both the Km and the Vmax of FAAH

Arachidonoyl Serotonin – 50 mg

Brand:
Cayman
CAS:
187947-37-1
Storage:
-80
UN-No:
De Minimis - 1231 / 3

Arachidonoyl serotonin is an inhibitor of fatty acid amide hydrolase (FAAH), the enzyme responsible for inactivation of anandamide and other endogenous cannabinoids. It inhibits the FAAH activity isolated from mouse neuroblastoma cells with an IC50 value of 12 µM. Both the Km and the Vmax of the enzyme are affected, indicating the Arachidonoyl serotonin is a very tight binding, competitive inhibitor of FAAH. Arachidonoyl serotonin does not inhibit cPLA2 and is essentially devoid of cannabimimetic activity.{6644}  

 

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SKU: 70665 - 50 mg Category:

Description

An inhibitor of FAAH attenuating the FAAH activity from mouse neuroblastoma cells with an IC50 value of 12 µM; alters both the Km and the Vmax of FAAH, indicating that it is a very tight binding, competitive inhibitor; does not inhibit cPLA2 and is essentially devoid of cannabimimetic activity

Formal name: N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide

Synonyms:  AA-5HT

Molecular weight: 462.7

CAS: 187947-37-1

Purity: ≥98%

Formulation: A solution in methyl acetate

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