An analog of AEA that exhibits weak or no binding to the human CB1 receptor (Ki >1 µM); inhibits rat glial gap junction cell-cell communication at a concentration of 50 µM

Arachidonoyl-N,N-dimethyl amide – 5 mg

Brand:
Cayman
CAS:
45280-17-9
Storage:
-20
UN-No:
De Minimis - 1231 / 3

Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N,N-dimethyl amide is an analog of anandamide that exhibits weak or no binding to the human central cannabinoid (CB1) receptor (Ki >1 µM).{9580} It inhibits rat glial gap junction cell-cell communication 100% at a concentration of 50 µM.{8122}  

 

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SKU: 10007293 - 5 mg Category:

Description

An analog of AEA that exhibits weak or no binding to the human CB1 receptor (Ki >1 µM); inhibits rat glial gap junction cell-cell communication at a concentration of 50 µM

Formal name: N,N-dimethyl-5Z,8Z,11Z,14Z-eicosatetraenamide

Synonyms:  Arachidonic Acid-N,N-dimethyl amide

Molecular weight: 331.5

CAS: 45280-17-9

Purity: ≥98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Lipids|Fatty Amides||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids

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