An internal standard for the quantification of AEA by GC- or LC-MS

Arachidonoyl Ethanolamide-d4 – 1 mg

Brand:
Cayman
CAS:
946524-40-9
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Arachidonoyl ethanolamide-d4 (AEA-d4) contains four deuterium atoms at the hydroxyethyl 1,1′,2, and 2′ positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain.{1134} It is an endogenous cannabinoid neurotransmitter that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors and mimics the pharmacologic effects of Δ9-THC.{2713} AEA inhibits the specific binding of [3H]-HU-243 to synaptosomal membranes with a Ki value of 52 nM, compared to 46 nM for Δ9-THC.{1134}  

 

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SKU: 10011178 - 1 mg Category:

Description

An internal standard for the quantification of AEA by GC- or LC-MS

Formal name: N-(2-hydroxyethyl-1,1,2,2-d4)-5Z,8Z,11Z,14Z-eicosatetraenamide

Synonyms:  AEA-d4|Anandamide-d4

Molecular weight: 351.6

CAS: 946524-40-9

Purity: ≥99% deuterated forms (d1-d4)

Formulation: A solution in ethanol

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Fatty Amides||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors||Research Area|Neuroscience|Cannabinoid Research|Endocannabinoids

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