A reversible inhibitor of serine proteases such as trypsin (Ki = 0.06 pM)

Aprotinin – 100 mg

Brand:
Cayman
CAS:
9087-70-1
Storage:
4
UN-No:
Non-Hazardous - /

Aprotinin is a reversible inhibitor of serine proteases such as trypsin (Ki = 0.06 pM), chymotrypsin (Ki = 9.5 nM), and kallikrein (Ki = 0.8 nM).{23496} It is a much weaker inhibitor of thrombin (Ki = 0.1-0.8 mM) and trypsinogen (Ki = 2 µM).{23496} Aprotinin also competitively inhibits nNOS and iNOS with Ki values of 50 and 78 µM, respectively.{9516} Aprotinin is widely used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest.  

 

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Description

A reversible inhibitor of serine proteases such as trypsin (Ki = 0.06 pM), chymotrypsin (Ki = 9.5 nM), and kallikrein (Ki = 0.8 nM); widely used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest

Formal name:

Synonyms:  Bovine Pancreatic Trypsin Inhibitor|BPTI

Molecular weight: 6,511.40

CAS: 9087-70-1

Purity: ≥95-100%

Formulation: A white to off-white crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Nitric Oxide Synthases||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases

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