Description
Histone H2AX, a variant of the nucleosome core histone H2A, undergoes phosphorylation on serine 139 in response to DNA damage, particularly when the damage involves formation of double-strand breaks. Phosphorylated H2AX is also termed γH2AX. Induction of γH2AX in cells exposed to genotoxic agents is considered a sensitive and specific reporter of DNA damage.{32236} This antibody reacts to γH2AX when phosphorylated at Ser139 and does not detect other phosphorylated histones.
Synonyms:
Immunogen: A phospho-peptide corresponding to γH2AX (phospho-Ser139)
Formulation: 100 µg protein A affinity-purified antibody from an animal origin–free culture supernatant
Isotype: IgG
Applications: ELISA, ICC, Multiplex, and WB
Origin:
Stability: 365 days
Application|ELISA||Application|Immunocytochemistry||Application|Multiplex||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Histones/Histone Peptides|Phosphorylated||Research Area|Epigenetics, Transcription, & Translation|Writers|Phosphorylation
