A weak antagonist of α1-adrenoceptors

Anisodamine – 1 g

Brand:
Cayman
CAS:
17659-49-3
Storage:
-20
UN-No:
Non-Hazardous - /

Anisodamine is a natural tropane alkaloid shown to be a weak antagonist of α1-adrenoceptors, blocking WB-4101 and clonidine (Item No. 15949) binding in brain membrane preparations with pKi values of 2.63 and 1.61, respectively.{31352} Anisodamine also has antioxidant effects that may protect against free radical-induced cellular damage.{31351} Anisodamine is predominantly found in the roots of A. tanguticus, which is used in traditional Chinese medicine for topical applications.{31350}  

 

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Description

A weak antagonist of α1-adrenoceptors, blocking WB-4101 and clonidine binding in brain membrane preparations with pKi values of 2.63 and 1.61, respectively; also has antioxidant effects

Formal name: αS-(hydroxymethyl)-benzeneacetic acid, 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

Synonyms:  6-hydroxy Hyoscyamine

Molecular weight: 305.4

CAS: 17659-49-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area

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