A degradation product of erythromycin; formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo; is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml

Anhydroerythromycin A – 5 mg

Brand:
Cayman
CAS:
23893-13-2
Storage:
-20
UN-No:
Non-Hazardous - /

Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin (Item No. 16486).{46271,46272} It is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively).{46273} It also inhibits steroid 6β-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.{46274}  

 

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SKU: 27960 - 5 mg Category:

Description

A degradation product of erythromycin; formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo; is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively); inhibits steroid 6β-hydroxylase activity associated with CYP3A in human liver microsomes

Formal name: 9-deoxo-6,12-dideoxy-6,9:9,12-diepoxy-erythromycin

Synonyms:  BRL 46355ER|Erythromycin Anhydride

Molecular weight: 715.9

CAS: 23893-13-2

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antibiotics|Macrolides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Toxicology|Drug Metabolism|Cytochrome P450

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