A phenylpropanoid with diverse biological activities; decreases the production of ROS in and increases survival of primordial follicles in isolated goat ovarian fragments at 30 µg/ml; reduces paw swelling and the number of serum and synovial leukocytes

Anethol – 1 g

Brand:
Cayman
CAS:
104-46-1
Storage:
-20
UN-No:
Non-Hazardous - /

Anethol is a phenylpropanoid that has been found in anise and fennel oils and has diverse biological activities.{58136,58135,58137,58138} It decreases the production of reactive oxygen species (ROS) in and increases survival of primordial follicles in isolated goat ovarian fragments when used at a concentration of 30 µg/ml.{58136} Anethol (62.5, 125, and 250 mg/kg) reduces paw swelling and the number of serum and synovial leukocytes, as well as prevents joint cartilage destruction in a rat model of adjuvant-induced arthritis.{58135} It reduces TNF-α production in a rat model of LPS-induced periodontitis.{58137} Anethol (125, 250, and 500 mg/kg) attenuates mechanical and thermal hyperalgesia in a mouse model of neuropathic pain induced by chronic constriction injury (CCI).{58138}  

 

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Description

A phenylpropanoid with diverse biological activities; decreases the production of ROS in and increases survival of primordial follicles in isolated goat ovarian fragments at 30 µg/ml; reduces paw swelling and the number of serum and synovial leukocytes, as well as prevents joint cartilage destruction in a rat model of adjuvant-induced arthritis at 62.5, 125, and 250 mg/kg; reduces TNF-α production in a rat model of LPS-induced periodontitis; attenuates mechanical and thermal hyperalgesia in a mouse model of CCI-induced neuropathic pain at 125, 250, and 500 mg/kg

Formal name: 1-methoxy-4-(1-propen-1-yl)-benzene

Synonyms:  p-Anthole|p-Propenylanisole|NSC 4018

Molecular weight: 148.2

CAS: 104-46-1

Purity: ≥98%

Formulation: A crystalline solid

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