An inhibitor of cAMP phosphodiesterases that reduces platelet production by reversibly blocking late-stage megakaryocyte maturation

Anagrelide (hydrochloride) – 250 mg

Brand:
Cayman
CAS:
58579-51-4
Storage:
-20
UN-No:
Non-Hazardous - /

Anagrelide is a synthetic quinazoline derivative that reduces platelet production by reversibly blocking late-stage megakaryocyte maturation.{33598} It has been shown to prevent platelet aggregation induced by either ADP or collagen and to inhibit platelet cAMP phosphodiesterases.{33599}  

 

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Description

An inhibitor of cAMP phosphodiesterases that reduces platelet production by reversibly blocking late-stage megakaryocyte maturation

Formal name: 6,7-dichloro-1,5-dihydro-imidazo[2,1-b]quinazolin-2(3H)-one, monohydrochloride

Synonyms:  BL 4162A|BMY 26538-01

Molecular weight: 292.6

CAS: 58579-51-4

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Phosphodiesterases||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis||Research Area|Cell Biology|Cell Signaling|cAMP Signaling

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