A broad spectrum antifungal agent (MICs = 0.25-1 μg/mL against T. rubrum

AN-2690 – 5 g

Brand:
Cayman
CAS:
174671-46-6
Storage:
-20
UN-No:
Non-Hazardous - /

AN-2690 is a broad spectrum antifungal agent with MIC values ranging from 0.25-1 μg/mL against T. rubrum, T. mentagrophytes, C. albicans, C. neoformans, and A. fumigatus.{41073} It inhibits tRNA aminoacylation (IC50 = 2.1 μM) and hydrolysis of Ile-tRNALeu in a dose-dependent manner in vitro.{41074} Formulations containing AN-2690 are under clinical investigation for the treatment of onychomycosis.  

 

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SKU: 23101 - 5 g Category:

Description

A broad spectrum antifungal agent (MICs = 0.25-1 μg/mL against T. rubrum, T. mentagrophytes, C. albicans, C. neoformans, and A. fumigatus); inhibits tRNA aminoacylation (IC50 = 2.1 μM) and hydrolysis of Ile-tRNALeu in a dose-dependent manner

Formal name: 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole

Synonyms:  Tavaborole

Molecular weight: 151.9

CAS: 174671-46-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antifungals||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Aspergillosis||Research Area|Infectious Disease|Fungal Diseases|Candidiasis||Research Area|Infectious Disease|Fungal Diseases|Ringworm

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