A histamine H2 receptor agonist (pD2 = 6.21 in isolated guinea pig atrium); selective for H2 over H3 receptors (pD2 = 4.7 in isolated guinea pig ileum); increases heart rate in spontaneously beating isolated guinea pig atrium (pD2 = 6.72) and decreases CCK octapeptide-induced contractions in isolated guinea pig gallbladder strips; increases levels of sheep red blood cell-induced production of IgG and IgM antibodies in rabbit serum at 10 µg/kg twice per day

Amthamine (hydrobromide) – 10 mg

Brand:
Cayman
CAS:
142457-00-9
Storage:
-20
UN-No:
Non-Hazardous - /

Amthamine is a histamine H2 receptor agonist (pD2 = 6.21 in isolated guinea pig atria).{48758} It is selective for H2 over H3 receptors (pD2 = 4.7 in isolated guinea pig ileum). Amthamine increases heart rate in spontaneously beating isolated guinea pig atria (pD2 = 6.72) and decreases contractions induced by cholecystokinin (CCK) octapeptide in a dose-dependent manner in isolated guinea pig gallbladder strips.{48759,48760} It increases sheep red blood cell-induced production of IgG and IgM antibodies in rabbit serum when administered at a dose of 10 µg/kg twice per day.{47697}  

 

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SKU: 29503 - 10 mg Category:

Description

A histamine H2 receptor agonist (pD2 = 6.21 in isolated guinea pig atrium); selective for H2 over H3 receptors (pD2 = 4.7 in isolated guinea pig ileum); increases heart rate in spontaneously beating isolated guinea pig atrium (pD2 = 6.72) and decreases CCK octapeptide-induced contractions in isolated guinea pig gallbladder strips; increases levels of sheep red blood cell-induced production of IgG and IgM antibodies in rabbit serum at 10 µg/kg twice per day

Formal name: 2-amino-4-methyl-5-thiazoleethanamine, dihydrobromide

Synonyms: 

Molecular weight: 319.1

CAS: 142457-00-9

Purity: ≥95%

Formulation: A crystalline solid

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