An antifungal; active against isolates of T. rubrum

Amorolfine (hydrochloride) – 500 mg

Brand:
Cayman
CAS:
78613-38-4
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Amorolfine is an antifungal.{41490} It is active against isolates of T. rubrum, T. mentagrophytes, and C. albicans (MIC90s = 4-15, 4-60, and ≤30-500 ng/ml, respectively). It inhibits the growth of T. mentagrophytes and T. rubrum by 33.7 and 38.5%, respectively, in an in vitro bovine hoof model of onychomycosis.{36951} Amorolfine also decreases the fungal burden in a rabbit model of onychomycosis when used as a 5% nail lacquer.{36952} Formulations containing amorolfine have been used in the treatment of fungal infections of the toe- or fingernails.  

 

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SKU: 26077 - 500 mg Category:

Description

An antifungal; active against isolates of T. rubrum, T. mentagrophytes, and C. albicans (MIC90s = 4-15, 4-60, and ≤30-500 ng/ml, respectively); inhibits the growth of T. mentagrophytes and T. rubrum by 33.7 and 38.5%, respectively, in an in vitro bovine hoof model of onychomycosis; decreases the fungal burden in a rabbit model of onychomycosis when used as a 5% nail lacquer

Formal name: (2R,6S)-rel-4-[3-[4-(1,1-dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine, monohydrochloride

Synonyms:  Ro 14-4767/002

Molecular weight: 354

CAS: 78613-38-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antifungals||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Candidiasis||Research Area|Infectious Disease|Fungal Diseases|Ringworm

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