A reversible inhibitor of AP-N/CD13 (IC50 = 25 μM); selective for AP-N/CD13 over MMP-9

Aminopeptidase N Inhibitor – 1 mg

Brand:
Cayman
CAS:
596108-59-7
Storage:
-20
UN-No:
Non-Hazardous - /

Aminopeptidase N (AP-N) inhibitor is a reversible inhibitor of AP-N/CD13 (IC50 = 25 μM).{39592} It is selective for AP-N/CD13 over matrix metalloproteinase-9 (MMP-9), angiotensin converting enzyme (ACE), neutral endopeptidase (NEP), γ-glutamyl transpeptidase, and the serine proteases dipeptidyl peptidase 4 (DPP-4) and cathepsin G at a concentration of 1 mM. AP-N inhibitor is non-cytotoxic to U937 cells at a concentration of 100 μM.  

 

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SKU: 24307 - 1 mg Category:

Description

A reversible inhibitor of AP-N/CD13 (IC50 = 25 μM); selective for AP-N/CD13 over MMP-9, ACE, NEP, γ-glutamyl transpeptidase, DPP-4, and cathepsin G; non-cytotoxic to U937 cells (100 μM),

Formal name: 3-nitro-2-(2-nitrophenyl)-4-oxo-4H-1-benzopyran-8-acetic acid

Synonyms:  AP-N Inhibitor

Molecular weight: 370.3

CAS: 596108-59-7

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Cell Biology|Proteolysis

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