An aromatase inhibitor (IC50 = 7.5 µM); inhibits estrogen synthesis

Aminoglutethimide – 1 g

Brand:
Cayman
CAS:
125-84-8
Storage:
-20
UN-No:
Non-Hazardous - /

Aminoglutethimide is an aromatase inhibitor (IC50 = 7.5 µM).{27484} Aromatase inhibitors, including aminoglutethimide, inhibit estrogen synthesis via aromatase, suppressing estrogen levels in post-menopausal women. Formulations containing aromatase inhibitors have been used to treat estrogen receptor-positive breast cancer in post-menopausal women.{22657,11203}  

 

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Description

An aromatase inhibitor (IC50 = 7.5 µM); inhibits estrogen synthesis, suppressing estrogen levels in post-menopausal women

Formal name: 3-(4-aminophenyl)-3-ethyl-2,6-piperidinedione

Synonyms:  DL-Aminoglutethimide|NSC 330915

Molecular weight: 232.3

CAS: 125-84-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cancer

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